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Z-Val-Pro-OEt, also known as N-benzyloxycarbonyl-L-valine-L-proline ethyl ester, is a peptide derivative that belongs to the class of chemical compounds called protected amino acids. It is a synthetic compound used in organic synthesis and peptide chemistry, particularly in the solid-phase peptide synthesis (SPPS) technique. The "Z" group in its name refers to the benzyloxycarbonyl (Z) protecting group, which is used to prevent unwanted side reactions during peptide synthesis. The "Val" and "Pro" abbreviations represent the amino acids L-valine and L-proline, respectively, while "OEt" signifies the ethyl ester group attached to the carboxylic acid moiety. Z-Val-Pro-OEt is a valuable building block for the synthesis of various peptide sequences and has applications in pharmaceutical research, drug development, and the study of protein structure and function.

20790-63-0

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20790-63-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 20790-63-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,7,9 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 20790-63:
(7*2)+(6*0)+(5*7)+(4*9)+(3*0)+(2*6)+(1*3)=100
100 % 10 = 0
So 20790-63-0 is a valid CAS Registry Number.

20790-63-0Downstream Products

20790-63-0Relevant academic research and scientific papers

KINETICS OF THE ALKALINE HYDROLYSIS OF SEVERAL N-BENZYLOXYCARBONYLDIPEPTIDE METHYL AND ETHYL ESTERS

Hoogwater, D. A.,Peereboom, M.

, p. 5325 - 5332 (2007/10/02)

The reaction rates of the alkaline hydrolysis of synthesized N-protected dipeptide methyl and ethyl esters were studied systematically.From the kinetic data the energies of activation, the pre-exponential factors and the reference values at 40 deg C were calculated.The rate of hydrolysis shows to be strongly dependent on the C-terminal amino acid in the sequence Gly >> Ala/Met/Phe > Leu >> Val/Pro.Surprisingly the N-terminal amino acid also exerts an effect, but in a different sequence.N-Terminal Phe in particular shows a relative accelerating effect.Remarkable is the significantly faster ester hydrolysis of glycine containing dipeptide ethyl esters in ethanol/water compared to the corresponding methyl esters in methanol/water.

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