207915-26-2

Basic information

• Product Name: (S)-2-((Z)-(R)-3-Benzyloxycarbonyl-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 207915-26-2
• Molecular Weight: 435.563
• Mol File: 207915-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((Z)-(R)-3-Benzyloxycarbonyl-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((Z)-(R)-3-Benzyloxycarbonyl-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester(207915-26-2)
• EPA Substance Registry System: (S)-2-((Z)-(R)-3-Benzyloxycarbonyl-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester(207915-26-2)

Safety Data

• Hazardous Substances Data: 207915-26-2(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2612-30-8 2-benzyl-1,3-propanediol 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 207915-21-7 (S)-2-((Z)-3-Benzyl-4-triisopropylsilanyloxy-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 207915-24-0 (S)-2-((Z)-(R)-3-Carboxy-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 207915-22-8 (S)-2-((Z)-(R)-3-Hydroxymethyl-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 207915-18-2 Methanesulfonic acid 2-benzyl-3-triisopropylsilanyloxy-propyl ester 
• 207915-19-3 (2-Iodomethyl-3-phenyl-propoxy)-triisopropyl-silane 
• 207915-17-1 2-Benzyl-3-triisopropylsilanyloxy-propan-1-ol 
• 115655-70-4 (S) tert-butyl 2-(1H-imidazole-1-carbonyl)pyrrolidine-1-carboxylate 
• 607-81-8 diethyl 2-benzylmalonate 
• 115186-37-3 tert-butyl (2S)-2-{[N-methoxy(N-methyl)amino]carbonyl}pyrrolidine-1-carboxylate 
• 69610-41-9 Boc-L-Pro-H 

Relevant articles and documents

Novel peptide isosteres that were designed to inhibit the binding of the HIV surface glycoprotein (gp120) to the T cell surface glycoprotein CD4

The cis- and trans-isomers of (2S)-2-[3′(RS)-3′-benzyl-3′-benzyloxycarbonylprop-1′- enyl]-N-methoxycarbonylcarbonylpyrrolidines have been prepared from a Wittig reaction between (S)-N-Boc-prolinal and the phosphorus ylide from (2RS)-3-iodo-2-benzyl-1-triisopropylsilyloxypropane. In addition, (2S)-N-methoxycarbonylcarbonyl-2-[(3′RS)-1-oxo-3′-benzyl-3′- benzyloxycarbonylpropyl]pyrrolidine was prepared from the cis-alkene produced in the Wittig reaction. These were intended as peptide isosteres of the known inhibitors of HIV-lymphocyte binding N-methoxycarbonylcarbonylprolylphenylalanyl benzyl esters, but did not possess such activity.