207985-69-1

Upstream product

• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 

Downstream Products

• 207985-90-8 (S)-2-[((R)-1-Benzyloxycarbonylamino-3-methyl-butyl)-methoxy-phosphinoyloxy]-3-[3-(tert-butoxycarbonylamino-methyl)-phenyl]-propionic acid methyl ester 
• 207985-92-0 (S)-3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-N-[(R)-1-({(S)-2-[3-(tert-butoxycarbonylamino-methyl)-phenyl]-1-methoxycarbonyl-ethoxy}-methoxy-phosphoryl)-3-methyl-butyl]-succinamic acid tert-butyl ester 
• 207985-93-1 (S)-N-[(R)-1-({(S)-2-[3-(tert-Butoxycarbonylamino-methyl)-phenyl]-1-methoxycarbonyl-ethoxy}-methoxy-phosphoryl)-3-methyl-butyl]-3-[(S)-3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-succinamic acid tert-butyl ester 
• 207985-91-9 (S)-3-Benzyloxycarbonylamino-N-[(R)-1-({(S)-2-[3-(tert-butoxycarbonylamino-methyl)-phenyl]-1-methoxycarbonyl-ethoxy}-methoxy-phosphoryl)-3-methyl-butyl]-succinamic acid tert-butyl ester 
• 207985-94-2 (S)-N-((R)-1-{[(S)-2-(3-Aminomethyl-phenyl)-1-methoxycarbonyl-ethoxy]-methoxy-phosphoryl}-3-methyl-butyl)-3-[(S)-3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-succinamic acid 
• 207985-96-4 (S)-3-Amino-N-[(R)-1-({(S)-2-[3-(tert-butoxycarbonylamino-methyl)-phenyl]-1-methoxycarbonyl-ethoxy}-methoxy-phosphoryl)-3-methyl-butyl]-succinamic acid tert-butyl ester 

Relevant academic research and scientific papers

Macrocyclic inhibitors of penicillopepsin. 3. Design, synthesis and evaluation of an inhibitor bridged between P2 and P1'

Through application of a thorough design and modeling protocol, the macrocyclic peptidyl phosphonate 5 was derived from the bound structure of an acyclic inhibitor of penicillopepsin, 4, by linking the P1' and P2 side chains; the acyclic analogues 6 and 7