208167-21-9Relevant articles and documents
NOVEL NAPHTHYRIDINE DERIVATIVES
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, (2008/06/13)
Naphthyridine derivative of the formula: wherein Ring A is substituted or unsubstituted pyridine ring, X is ―N(R2)―CO― (R2is H, alkyl, substituted alkyl, etc.), Z is a direct bond, ―NH―, C1-2alkylene, or ―CH=CH―, Y is aromatic group or substituted aromatic group, L is alkyl, substituted alkyl, aromatic group or substituted aromatic group, or an acid addition salt thereof, these compounds exhibiting acyl-CoA: cholesterol acyl transferase inhibitory activity, and being useful as an agent for prophylaxis or treatment of hyperlipidemia, atherosclerosis, and related diseases thereof.