208255-34-9Relevant academic research and scientific papers
A series of C-terminal amino alcohol dipeptide Aβ inhibitors
Garofalo, Albert W.,Wone, David W.G.,Phuc, Angela,Audia, James E.,Bales, Cheryl A.,Dovey, Harry F.,Dressen, Darren B.,Folmer, Beverly,Goldbach, Erich G.,Guinn, Ashley C.,Latimer, Lee H.,Mabry, Thomas E.,Nissen, Jeffrey S.,Pleiss, Michael A.,Sohn, Stephen,Thorsett, Eugene D.,Tung, Jay S.,Wu, Jing
, p. 3051 - 3053 (2007/10/03)
Potent, small molecule Aβ inhibitors have been prepared that incorporate an alanine core bracketed by an N-terminal arylacetyl group and various C-terminal amino alcohols. The compounds exhibit stereospecific inhibition as demonstrated in an in vitro assa
