208259-66-9Relevant articles and documents
Small hydroxyethylene-based peptidomimetics inhibiting both HIV-1 and C. albicans aspartic proteases
Tossi, Alessandro,Benedetti, Fabio,Norbedo, Stefano,Skrbec, Damiano,Berti, Federico,Romeo, Domenico
, p. 4719 - 4727 (2003)
We have extended a highly flexible method for rapidly assembling aspartic protease inhibitors to produce symmetric and asymmetric monohydroxyethylene peptidomimetics. This method is based on the prior synthesis of the central non-cleavable peptide-bond is