208264-53-3

Basic information

• Product Name: 2-acetyl-4-bromothiazole
• Synonyms: 2-acetyl-4-bromothiazole;1-(4-bromo-1,3-thiazol-2-yl)ethanone
• CAS NO: 208264-53-3
• Molecular Formula: C₅H₄BrNOS
• Molecular Weight: 206.06036
• Mol File: 208264-53-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 279.2±32.0 °C(Predicted)
• Appearance: /
• Density: 1.719±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.72±0.10(Predicted)
• CAS DataBase Reference: 2-acetyl-4-bromothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetyl-4-bromothiazole(208264-53-3)
• EPA Substance Registry System: 2-acetyl-4-bromothiazole(208264-53-3)

Safety Data

• Hazardous Substances Data: 208264-53-3(Hazardous Substances Data)

Usage

Uses

2-Acetyl-4-bromothiazole is the derivative of 2,4-Dibromothiazole (D426050), which is an intermediate used in the preparation of various 2,4-disubstituted thiazole derivatives with biologically active properties such as survival motor neuron (SMN) protein modulators.

Upstream product

• 1696-20-4 4-acetylmorpholine 
• 4175-77-3 2,4-dibromo-1,3-thiazole 

Relevant articles and documents

D I H YD ROOXAZO LE AND THIOUREA DERIVATIVES MODULATING THE NLRP3 INFLAMMASOME PATHWAY

The invention relates to novel compounds of formulae (I') and (II') for the treatment, alleviation or prevention of diseases, disorders and abnormalities which are responsive to the modulation or inhibition of the activation of a component of the NLRP3 in

CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME

The present disclosure provides, in part, cyclic sulfamide compounds, and pharmaceutical compositions thereof, useful as modulators of Hepatitis B (HBV) core protein, and methods of treating Hepatitis B (HBV) infection.

Highly efficient, multigram and enantiopure synthesis of (S)-2-(2,4′-bithiazol-2-yl)pyrrolidine

(S)-2-(4-Bromo-2,4′-bithiazole)-1-(tert-butoxycarbonyl)pyrrolidine ((S)-1) was obtained as a single enantiomer and in high yield by means of a two-step modified Hantzsch thiazole synthesis reaction when bromoketone 3 and thioamide (S)-4 were used. Further conversion of (S)-1 into trimethyltin derivative (S)-2 broadens the scope for further cross-coupling reactions.