208347-61-9Relevant academic research and scientific papers
Preparation and evaluation of diarylalkynes as antitumour agents
Hadfield, John A.,McGown, Alan T.
, p. 1421 - 1431 (1998)
A series of diarylalkynes have been synthesised and tested for anti- tumour activity.
Synthesis and biological evaluation of cis-combretastatin analogs and their novel 1,2,3-triazole derivatives
Pati, Hari N.,Wicks, Martha,Holt Jr., Herman L.,LeBlanc, Regan,Weisbruch, Paul,Forrest, Lori,Lee, Moses
, p. 117 - 120 (2007/10/03)
Three cis-combretastatin analogs (8-10) and three novel 1,2,3-triazole derivatives (5-7) have been synthesized. The cis-combretastatins were prepared from selective hydrogenation of the corresponding alkyne. Reaction of the alkyne intermediates with benzy
