208396-50-3

Basic information

• Product Name: (E)-(4S,5R)-4-Acetoxy-2-acetylamino-5-(S)-aziridin-2-yl-3-bromo-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester
• Synonyms: (E)-(4S,5R)-4-Acetoxy-2-acetylamino-5-(S)-aziridin-2-yl-3-bromo-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester
• CAS NO: 208396-50-3
• Molecular Weight: 485.332
• Mol File: 208396-50-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-(4S,5R)-4-Acetoxy-2-acetylamino-5-(S)-aziridin-2-yl-3-bromo-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(4S,5R)-4-Acetoxy-2-acetylamino-5-(S)-aziridin-2-yl-3-bromo-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester(208396-50-3)
• EPA Substance Registry System: (E)-(4S,5R)-4-Acetoxy-2-acetylamino-5-(S)-aziridin-2-yl-3-bromo-5-(4-methoxy-benzyloxy)-pent-2-enoic acid methyl ester(208396-50-3)

Safety Data

• Hazardous Substances Data: 208396-50-3(Hazardous Substances Data)

Upstream product

• 207679-33-2 (S)-2-[(E)-(1R,2S)-2-Acetoxy-4-acetylamino-3-bromo-1-(4-methoxy-benzyloxy)-4-methoxycarbonyl-but-3-enyl]-aziridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 2746-25-0 p-Methoxybenzyl bromide 
• 112531-79-0 (3R,4R)-4-(methoxymethoxy)hexa-1,5-dien-3-ol 
• 207679-32-1 (S)-2-[(Z)-(1R,2R)-2-Acetoxy-4-acetylamino-1-(4-methoxy-benzyloxy)-4-methoxycarbonyl-but-3-enyl]-aziridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 207679-30-9 (S)-2-[(Z)-(1R,2R)-2-Acetoxy-4-acetylamino-1-(4-methoxy-benzyloxy)-4-methoxycarbonyl-but-3-enyl]-aziridine-1-carboxylic acid benzyl ester 
• 207679-40-1 Methanesulfonic acid (1R,2S,3R)-1-(benzyloxycarbonylamino-methyl)-2-(4-methoxy-benzyloxy)-3-methoxymethoxy-pent-4-enyl ester 
• 207679-27-4 Acetic acid (1R,2S,3R)-4-benzyloxycarbonylamino-3-methanesulfonyloxy-2-(4-methoxy-benzyloxy)-1-vinyl-butyl ester 
• 207679-41-2 Methanesulfonic acid (1R,2S,3R)-1-(benzyloxycarbonylamino-methyl)-3-hydroxy-2-(4-methoxy-benzyloxy)-pent-4-enyl ester 
• 207679-26-3 [(2R,3R,4R)-2-Hydroxy-3-(4-methoxy-benzyloxy)-4-methoxymethoxy-hex-5-enyl]-carbamic acid benzyl ester 
• 207679-29-6 (S)-2-[(1R,2S)-2-Acetoxy-1-(4-methoxy-benzyloxy)-3-oxo-propyl]-aziridine-1-carboxylic acid benzyl ester 
• 207679-28-5 (S)-2-[(1R,2R)-2-Acetoxy-1-(4-methoxy-benzyloxy)-but-3-enyl]-aziridine-1-carboxylic acid benzyl ester 
• 207679-24-1 (2R,3R,4R)-1-Azido-3-(4-methoxy-benzyloxy)-4-methoxymethoxy-hex-5-en-2-ol 
• 207679-25-2 (2R,3R,4R)-1-Amino-3-(4-methoxy-benzyloxy)-4-methoxymethoxy-hex-5-en-2-ol 
• 207679-23-0 (R)-2-[(1S,2R)-1-(4-Methoxy-benzyloxy)-2-methoxymethoxy-but-3-enyl]-oxirane 

Relevant articles and documents

Synthesis of naturally occurring antitumor agents: Stereocontrolled synthesis of the azabicyclic ring system of the azinomycins

Full details of the synthesis of the fully elaborated aziridino[1,2-a]pyrrolidine substructure 2 of the antitumor agents azinomycins A and B are reported. Stereoselective bromination of dehydroamino acid 4 provided control of olefin configuration in the f