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Angiotensinogen, a glycoprotein synthesized primarily in the liver, serves as the precursor to angiotensin, a peptide hormone pivotal in the regulation of blood pressure and fluid balance. Its cleavage by renin, an enzyme secreted by the kidneys, initiates a cascade that leads to the formation of angiotensin II, a potent vasoconstrictor with significant roles in blood pressure elevation, fluid retention, and the pathogenesis of cardiovascular diseases.

20845-02-7

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20845-02-7 Usage

Uses

Used in Pharmaceutical Industry:
Angiotensinogen is used as a therapeutic target for the development of drugs aimed at treating hypertension and other cardiovascular conditions. By modulating the renin-angiotensin system, drugs can effectively manage blood pressure and mitigate the risk of cardiovascular diseases.
Used in Research and Development:
Angiotensinogen is utilized as a key biomarker in research studies focused on understanding the pathophysiology of hypertension and cardiovascular diseases. It aids in the identification of novel therapeutic targets and the development of innovative treatment strategies.
Used in Diagnostic Applications:
Angiotensinogen levels can be measured in clinical settings to assess the risk of developing hypertension and cardiovascular diseases. Elevated levels of angiotensinogen may indicate the presence of underlying health conditions, guiding further diagnostic evaluations and treatment plans.
Used in Drug Delivery Systems:
Innovative drug delivery systems are being developed to target angiotensinogen and the renin-angiotensin system, enhancing the efficacy and bioavailability of drugs used in the management of hypertension and cardiovascular diseases. These systems may include nanoparticles, liposomes, or other carriers designed to improve drug delivery and therapeutic outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 20845-02-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,4 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20845-02:
(7*2)+(6*0)+(5*8)+(4*4)+(3*5)+(2*0)+(1*2)=87
87 % 10 = 7
So 20845-02-7 is a valid CAS Registry Number.

20845-02-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name ANGIOTENSINOGEN

1.2 Other means of identification

Product number -
Other names TETRADECAPEPTIDE RENIN SUBSTRATE (HORSE)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20845-02-7 SDS

20845-02-7Upstream product

20845-02-7Downstream Products

20845-02-7Relevant academic research and scientific papers

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