208593-05-9

Basic information

• Product Name: (S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine
• CAS NO: 208593-05-9
• Molecular Weight: 423.535
• Mol File: 208593-05-9.mol

Chemical Properties

• CAS DataBase Reference: (S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine(208593-05-9)
• EPA Substance Registry System: (S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine(208593-05-9)

Safety Data

• Hazardous Substances Data: 208593-05-9(Hazardous Substances Data)

Usage

Uses

Used in Research and Development:
(S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine is used as a research compound for exploring its potential applications in various scientific fields due to its unique molecular structure and the presence of a phosphorus atom.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine may be utilized as a ligand or catalyst to facilitate specific chemical reactions, contributing to the development of new molecules and materials.
Used in Coordination Chemistry:
(S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine could be employed in coordination chemistry as a ligand to form complexes with metal ions, potentially leading to new insights into metal coordination and catalytic properties.
Used in Material Science:
(S)-diisopropyl(8,9,10,11,12,13,14,15-octahydro-3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)amine may also find applications in material science, where its unique structure could be leveraged to create novel materials with specific properties, such as improved conductivity, strength, or reactivity.

Upstream product

• 921-26-6 N,N-diisopropylphosphoramide dichloride 
• 39648-74-3 (S)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol 
• 108-18-9 diisopropylamine 
• 39648-74-3 (Ra)-5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diol 

Relevant articles and documents

Regioselective phosphorylation of: Myo -inositol with BINOL-derived phosphoramidites and its application for protozoan lysophosphatidylinositol

A regioselective phosphorylation method for myo-inositol was developed by utilizing readily preparable BINOL-derived phosphoramidites. The method also facilitated the complete separation of the diastereomeric products by simple chromatography. Based on this phosphorylation and Ni-catalyzed alkyl-alkyl cross-coupling reaction for long fatty acids, we achieved the first synthesis of a lysophosphatidylinositol, EhPIa having long fatty acid C30:1, as a partial structure of glycosylphosphatidylinositol (GPI) anchor from the cell membrane of a protozoa, Entamoeba histolytica.

Cobalt-Catalyzed Enantioselective Directed C-H Alkylation of Indole with Styrenes

A cobalt-chiral phosphoramidite catalyst promotes enantioselective imine-directed C2-alkylation of Boc-protected indoles with styrenes. The reaction affords 1,1-diarylethane products in moderate to good yields with good enantioselectivities under mild conditions. A deuterium-labeling experiment suggests that the enantioselectivity is controlled by both the styrene insertion and the C-C reductive elimination steps. (Chemical Equation Presented).

Enantioselective intramolecular hydroarylation of alkenes via directed C-H bond activation

(Chemical Equation Presented) Highly enantioselective catalytic intramolecular ortho-alkylation of aromatic imines containing alkenyl groups tethered at the meta position relative to the imine directing group has been achieved using [RhCl(coe)2]2 and chiral phosphoramidite ligands. Cyclization of substrates containing 1,1- and 1,2-disubstituted as well as trisubstituted alkenes were achieved with enantioselectivities >90% ee for each substrate class. Cyclization of substrates with Z-alkene isomers proceeded much more efficiently than substrates with E-alkene isomers. This further enabled the highly stereoselective intramolecular alkylation of certain substrates containing Z/E-alkene mixtures via a Rh-catalyzed alkene isomerization with preferential cyclization of the Z-isomer.