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5-Diethylamiloride is a chemical compound that belongs to the class of amiloride derivatives, which are known for their ability to inhibit sodium-proton exchangers, particularly the NHE1 isoform. This inhibition can lead to a reduction in intracellular pH, affecting various cellular processes. 5-Diethylamiloride is structurally similar to amiloride but with two ethyl groups attached to the 5-position of the molecule, which can enhance its potency and selectivity. It is used in scientific research to study the role of ion transport in cells and has potential applications in the development of drugs targeting ion channelopathies and related diseases.

2086-31-9

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2086-31-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2086-31-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,8 and 6 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2086-31:
(6*2)+(5*0)+(4*8)+(3*6)+(2*3)+(1*1)=69
69 % 10 = 9
So 2086-31-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H16ClN7O/c1-3-18(4-2)8-6(11)15-5(7(12)16-8)9(19)17-10(13)14/h3-4H2,1-2H3,(H2,12,16)(H4,13,14,17,19)

2086-31-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-N,N-diethylamiloride

1.2 Other means of identification

Product number -
Other names 2-Diethylamino-3-chlor-6-amino-5-(N-guanyl-carbamoyl)-pyrazin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2086-31-9 SDS

2086-31-9Upstream product

2086-31-9Downstream Products

2086-31-9Relevant academic research and scientific papers

N-pyrazinecarbonyl-N'-acylguanidines

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, (2008/06/13)

The case involves novel N-pyrazinecarbonyl-N'-acylguanidines and processes for preparing same. The N-pyrazinecarbonyl-N'-acylguanidines are eukalemic agents possessing diuretic and natriuretic properties.

N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same

-

, (2008/06/13)

The case involves novel N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same. The N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidines are excellent eukalemic agents possessing diuretic and natriuretic properties.

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