208772-23-0

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-Benzoxazolecarboxylic acid is used as a key building block for the synthesis of various pharmaceuticals and agrochemicals, due to its versatile chemical structure and potential biological activities.
Used in Material Science:
4-Benzoxazolecarboxylic acid is utilized in the development of new materials, capitalizing on its chemical properties and potential for innovative applications in material science.
Used as a Fluorescent Dye in Research:
In biological and chemical research, 4-Benzoxazolecarboxylic acid is employed as a fluorescent dye, enabling researchers to visualize and study various processes and interactions within complex systems.
Used in Antimicrobial Applications:
4-Benzoxazolecarboxylic acid is used as an antimicrobial agent, leveraging its inherent antimicrobial properties to combat various microorganisms.
Used in Antiviral Applications:
4-Benzoxazolecarboxylic acid is also used as an antiviral agent, harnessing its potential to inhibit viral replication and activity.
Used in Anti-Inflammatory Applications:
4-Benzoxazolecarboxylic acid is applied in anti-inflammatory treatments, owing to its capacity to reduce inflammation and associated symptoms.

Upstream product

• 149-73-5 trimethyl orthoformate 
• 548-93-6 3-hydroxyanthranilic acid 
• 906096-11-5 2-amino-3-hydroxybenzoic acid hydrobromide 
• 122-51-0 orthoformic acid triethyl ester 
• 603-81-6 2,3-diaminobenzoic acid 

Downstream Products

• 1610736-96-3 N-((1s,4s)-4-(2-(2'-((dimethylamino)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)benzo[d]oxazole-4-carboxamide trifluoroacetic acid salt 

Relevant academic research and scientific papers

Compound serving as IRAK inhibitor

The present invention relates to a compound suitable for the treatment of cancer and inflammatory diseases associated with interleukin-1 receptor associated kinase (IRAK), particularly relates to a compound serving as an IRAK4 inhibitor and a preparation

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

2-ALKYLBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS

Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds are useful in treating CINV, IBS-D and other diseases and conditions.

2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

Benzamide derivatives having a vasopressin antagonistic activity

This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc. and represented by general formula (I): wherein R1is aryl optionally substituted with lower alkoxy, etc., R2is lower alkyl, etc., R3is hydrogen, etc., A is NH, etc., E is etc., X is —CH═CH—, —CH═N—, or S, and Y is a condensed heterocyclic group, etc., and pharmaceutically acceptable salts thereof, to processes for preparation thereof and to a pharmaceutical composition comprising the same.

Benzimidazole compounds

Benzimidazole-4-carboxamide compounds (I) which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC 2.4.2.30), and which thereby can provide useful therapeutic compounds for use in conjunction with DNA-damaging cytotoxic drugs or radiotherapy to potentiate the effects of the latter. In formula (I), R and R' may each be selected independently from hydrogen, alkyl, hydroxyalkyl (e.g. CH2CH2OH), acyl (e.g. acetyl or benzoyl) or an optionally substituted aryl (e.g. phenyl) or aralkyl (e.g. benzyl or carboxybenzyl) group. R is generally a substituted phenyl group in the most preferred compounds. The compounds may also be used in the form of pharmaceutically acceptable salts or pro-drugs.