208844-93-3Relevant academic research and scientific papers
Synthesis of 2-deoxy-2-fluoro-phosphatidylinositol-4,5-bisphosphate and analoglies: Probes and modulators of the mammalian PI-PLCs
Aneja, Sarla G.,Ivanova, Pavlina T.,Aneja, Rajindra
, p. 1061 - 1064 (2007/10/03)
An approach to synthesis of 2-modified phosphatidylinositol-4,5- bisphosphates, which are substrate analogues useful as probes and modulators of the PI-PLC enzyme family, is described and illustrated for the dibutyl-2- deoxy-2-fluoro analogue, a probe designed for delineating substrate and PI- PLC interactions by X-ray crystallography.
