2089288-03-7

Basic information

• Product Name: AZD-1390
• Synonyms: AZD-1390
• CAS NO: 2089288-03-7
• Molecular Formula: C27H32FN5O2
• Molecular Weight: 477.5736832
• EINECS: -0
• Mol File: 2089288-03-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 617.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.224±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.22±0.10(Predicted)
• CAS DataBase Reference: AZD-1390(CAS DataBase Reference)
• NIST Chemistry Reference: AZD-1390(2089288-03-7)
• EPA Substance Registry System: AZD-1390(2089288-03-7)

Safety Data

• Hazardous Substances Data: 2089288-03-7(Hazardous Substances Data)

Usage

Uses

AZD 1390 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor.

Upstream product

• 104-58-5 3-piperidinopropan-1-ol 
• 953803-84-4 ethyl 6-bromo-4-chloro-7-fluoroquinoline-3-carboxylate 

Relevant articles and documents

DEUTERATED IMIDAZO[4,5-C]QUINOLIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER

The specification generally relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, where R1 has the meanings defined herein. The specification also relates to the use of compounds of Formula (I) and salts thereof to treat or prevent ATM mediated disease, including cancer. The specification further relates to pharmaceutical compositions comprising substituted imidazo[4,5- c]quinolin-2-one compounds and pharmaceutically acceptable salts thereof; and kits comprising such compounds and salts.