20894-24-0

Upstream product

• 20894-13-7 (+/-)-5-methyl-5-nitro-4-phenylhexan-2-one 
• 20894-11-5 4-methyl-4-nitro-1,3-diphenylpentan-1-one 

Downstream Products

• 21019-05-6 2,2,5-trimethyl-3t-phenyl-(5rH)-6-oxa-1-aza-bicyclo[3.1.0]hexane 
• 50455-69-1 5,5,7a-trimethyl-1,6-diphenyl-tetrahydro-pyrrolo[1,2-b][1,2,4]oxadiazole-2-thione 
• 139012-11-6 2-(2'-dimethylaminovinyl)-5,5-dimethyl-4-phenyl-1-pyrroline 1-oxide 
• 20894-31-9 2,2,5-trimethyl-3-phenyl-3,4-dihydro-2H-pyrrole 
• 91956-39-7 3-phenyl-2,2,5-trimethyl-2H-pyrrole 
• 122546-89-8 3-benzoyloxy-4-phenyl-2,5,5-trimethyl-1-pyrroline 
• 20894-13-7 (+/-)-5-methyl-5-nitro-4-phenylhexan-2-one 
• 89885-35-8 5-methyl-5-nitroso-4-phenylhexan-2-one 
• 81113-66-8 2,2,5-Trimethyl-3-phenyl-pyrrolidine 
• 119580-60-8 2,2,5,5-tetramethyl-3-phenylpyrrolidin-1-oxyl 
• 1373248-36-2 5-(3-bromo-prop-1-ynyl)-2,2,5-trimethyl-3-phenyl-pyrrolidin-1-yloxyl 
• 1373248-40-8 1-[3-(1-oxyl-2,5,5-trimethyl-4-phenyl-pyrrolidin-2-yl)-prop-2-ynyl]-pyrrolidin-2-one 
• 1373248-42-0 2,2,5-trimethyl-3-phenyl-5-(3-pyrrolidin-1-yl-prop-1-ynyl)-pyrrolidine 
• 1373248-44-2 1-[3-(2,5,5-trimethyl-4-phenyl-pyrrolidin-2-yl)prop-2-ynyl]pyrrolidin-2-one 

Relevant academic research and scientific papers

HYDROXYLAMINE COMPOUNDS AND METHODS OF THEIR USE

The present disclosure provides compounds that include hydroxylamines of formula (I) or (II), pharmaceutical compositions, and methods for their use. The methods utilize hydroxylamine compounds and/or their pharmaceutical compositions for the treatment of angiogenesis, hepatitis, complement-mediated pathologies, drusen-mediated pathologies, macular degeneration and certain other ophthalmic conditions, inflammation, arthritis, and related diseases and for the inhibition of complement activation.

CONJUGATE ADDITION WITH ORGANOMETALLICS AND NITRATION OF NITROXIDE (AMINOXYL) FREE RADICALS. SYNTHESIS OF POTENTIALLY USEFUL CROSS-LINKING SPIN LABEL REAGENTS

3-Metoxycarbonyl-2,2,5,5-tetramethyl-2,5-dihydropyrrol-1-oxyl (1) was converted with PhMgBr-CuI in a conjugate addition into 3-methoxycarbonyl-2,2,5,5-tetramethyl-4-phenylpyrrolidin-1-oxyl (2).Compound (2) was nitrated with concentrated H2SO4/HNO3 to give

Reduction electrochimique de γ-nitrocetones. Conditions experimentales d'acces a des derives de la pyrroline et de la pirrolidine

Optimal conditions for electrosynthesis, at a mercury cathode in hydroalcoholic media, of three classes of nitrogen heterocyclic compounds are set up from an exhaustive study of the electrochemical behaviour of γ-nitroketones 1 and their reduction product

Preparation de pyrrolines N-oxydes, pyrrolines et pyrrolidines par reduction electrochimique de γ-nitrocetones

Judiciously selected conditions of controlled potential electrolysis, at a mercury cathode in aqueous organic media, of γ-nitroketones result in quantitative yields of 1-pyrroline 1-oxides, pyrrolines or pyrrolidines.