15(R)-PROSTAGLANDIN E1, also known as 15-epi-Prostaglandin E1, is a naturally occurring prostaglandin that plays a significant role in various physiological processes. It is characterized by its unique chemical structure and biological activities, making it a subject of interest for scientific research and potential therapeutic applications.
20897-91-0
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Basic information
- Product Name: 15(R)-PROSTAGLANDIN E1
- Synonyms: 15-EPI PGE1;15(R)-PROSTAGLANDIN E1;9-OXO-11ALPHA,15R-DIHYDROXY-PROST-13E-EN-1-OIC ACID;(13E,15R)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid;15(R)-Prostaglandin E1;GMVPRGQOIOIIMI-CHCORRSHSA-N;15(R)-PGE1;9-oxo-11α,15R-dihydroxy-prost-13E-en-1-oic acid
- CAS NO:20897-91-0
- Molecular Formula: C20H34O5
- Molecular Weight: 354.48
- EINECS: N/A
- Product Categories: N/A
- Mol File: 20897-91-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 529.3±50.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.131±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 4.77±0.10(Predicted)
- CAS DataBase Reference: 15(R)-PROSTAGLANDIN E1(CAS DataBase Reference)
- NIST Chemistry Reference: 15(R)-PROSTAGLANDIN E1(20897-91-0)
- EPA Substance Registry System: 15(R)-PROSTAGLANDIN E1(20897-91-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 20897-91-0(Hazardous Substances Data)
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20897-91-0 Usage
Uses
Used in Pharmaceutical Research:15(R)-PROSTAGLANDIN E1 is used as a research compound for studying the kinetic properties of 15-hydroxyprostaglandin dehydrogenase, an enzyme involved in the metabolism of prostaglandins. This enzyme plays a crucial role in regulating the levels of bioactive prostaglandins in the body, which are involved in various physiological processes such as inflammation, blood clotting, and smooth muscle contraction.
Used in Conformational Analysis:
15(R)-PROSTAGLANDIN E1 is utilized as a tool in the conformational analysis of prostaglandins, which are a group of lipid compounds with diverse biological activities. Understanding the three-dimensional structure of these molecules is essential for elucidating their mode of action and for the development of new drugs that can modulate their effects.
Used in Active Site Studies:
This prostaglandin is also employed in the investigation of active sites, which are specific regions within enzymes or other proteins where substrate molecules bind and undergo chemical reactions. By studying the interactions between 15(R)-PROSTAGLANDIN E1 and its target proteins, researchers can gain insights into the molecular mechanisms underlying the biological activities of prostaglandins.
Used in Conformation-Action Relationship:
15(R)-PROSTAGLANDIN E1 is used to explore the relationship between the conformation (shape) of a molecule and its biological activity. This is particularly relevant in the context of drug design, as understanding how the structure of a molecule influences its function can guide the development of more effective and selective therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 20897-91-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,9 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.Calculate Digit Verification of CAS Registry Number 20897-91:
(7*2)+(6*0)+(5*8)+(4*9)+(3*7)+(2*9)+(1*1)=130
130 % 10 = 0
So 20897-91-0 is a valid CAS Registry Number.
20897-91-0Upstream product
20897-91-0Downstream Products
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15(R)-PROSTAGLANDIN E1
