2090-25-7Relevant articles and documents
High regioselectivity in the heterocyclization of β-oxonitriles to 4-oxothiazolidines: X-ray structure proof
Markovi?, Rade,Baranac, Marija,D?ambaski, Zdravko,Stojanovi?, Milovan,Steel, Peter J.
, p. 7803 - 7810 (2007/10/03)
Base-catalyzed reactions of β-oxonitriles 1 with diethyl mercaptosuccinate favour heterocyclization to afford 2-alkylidene-4-oxothiazolidines 3, rather than 2-alkylidene-4-oxo-1,3-thiazinanes 4. The observed regioselectivity is based on spectroscopic and experimental evidence, including a single-crystal X-ray structure determination.