209047-87-0

Upstream product

• 149578-28-9 2-(trimethylsilyl)ethyl N,N,N',N'-tetraisopropyl phosphorodiamidite 
• 14985-43-4 N-benzoyl-2',3'-di-O-benzoyladenosine 
• 209047-58-5 N-trityl-L-phenylalaninamide 
• 209047-49-4 N-benzoyl-2',3'-di-O-benzoyladenosine-5'-O-[2-(trimethylsilyl)ethyl N,N-diisopropylphosphoramidite] 

Relevant academic research and scientific papers

Synthesis of new aminoacyl-adenylate analogs having an N-acyl phosphoramidate linkage

New aminoacyl-adenylate analogs (aa-AMPNs), in which the oxygen atom of the mixed anhydride bond of aminoacyl-adenylates is replaced by an NH group, were synthesized by the reaction of an adenosine 5'-phosphoramidite derivative with appropriately protected amino acid amides. Among various reagents studied for activation of the 5'-phosphoramidite derivative, 5-(4- nitrophenyl)-1H-tetrazole was found to give N-acyl phosphoramidate derivatives in good yields.