20914-21-0

Basic information

• Product Name: butyl(phenyl)cyanamide
• CAS NO: 20914-21-0
• Molecular Formula: C₁₁H₁₄N₂
• Molecular Weight: 174.2423
• Mol File: 20914-21-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 301.5°C at 760 mmHg
• Flash Point: 122.9°C
• Density: 1.022g/cm³
• Vapor Pressure: 0.00105mmHg at 25°C
• Refractive Index: 1.551
• CAS DataBase Reference: butyl(phenyl)cyanamide(CAS DataBase Reference)
• NIST Chemistry Reference: butyl(phenyl)cyanamide(20914-21-0)
• EPA Substance Registry System: butyl(phenyl)cyanamide(20914-21-0)

Safety Data

• Hazardous Substances Data: 20914-21-0(Hazardous Substances Data)

Upstream product

• 13510-29-7 n-butylcyanamide 
• 591-50-4 iodobenzene 
• 108-86-1 bromobenzene 
• 1126-78-9 N-(n-butyl)aniline 
• 506-68-3 bromocyane 
• 861298-29-5 N-butyl-N-cyclobutylmethyl-aniline 

Downstream Products

• 93151-77-0 N_.O-Dibutyl-N-phenyl-isoharnstoff 

Relevant articles and documents

Transition-metal free N-arylation of cyanamides by diaryliodonium triflates in aqueous media

An operationally simple protocol is established for the synthesis of disubstituted cyanamides through the transition-metal free N-arylation of cyanamides by diaryliodonium triflates in aqueous media. Both alkyl and aryl cyanamides are well compatible with the mild reaction conditions. The one-pot synthesis of ureas is also possible through sequential arylation and hydrolysis of cyanamides, diaryliodonium triflates and H2O with good yields.

HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 -HYDROXYSTEROID DEHYDROGENASE

Disclosed is a compound which is useful as an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein X is O or S, a broken line and a wavy line represent the presence or the absence of a bond, (i) when a broken line represents the presence of a bond, a wavy line represents the absence of a bond, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, (ii) when a broken line represents the absence of a bond, a wavy line represents the presence of a bond, R1 and R4 are each independently hydrogen, halogen or the like, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, and R5 and R6 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like.