2092-90-2Relevant academic research and scientific papers
Design, synthesis and evaluation of novel 19F magnetic resonance sensitive protein tyrosine phosphatase inhibitors
Li, Yu,Xia, Guiquan,Guo, Qi,Wu, Li,Chen, Shizhen,Yang, Zhigang,Wang, Wei,Zhang, Zhong-Yin,Zhou, Xin,Jiang, Zhong-Xing
, p. 1672 - 1680 (2016)
Fluorine is a highly attractive element for both medicinal chemistry and imaging technologies. To facilitate protein tyrosine phosphatase (PTP)-targeted drug discovery and imaging-guided PTP research on fluorine, several highly potent and 19F MR sensitive PTP inhibitors were discovered through a structure-based focused library strategy.
