2H-1,2,4-Benzothiadiazine, 3-(methylthio)-, 1,1-dioxide, commonly known as methazolamide, is a carbonic anhydrase inhibitor with a wide range of therapeutic applications. It is characterized by its ability to reduce the production of aqueous humor in the eye, thereby lowering intraocular pressure and preventing optic nerve damage. Methazolamide also exhibits potential therapeutic effects in conditions such as heart failure and sickle cell disease, making it a versatile compound in the field of medicine.
20926-33-4
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Basic information
- Product Name: 2H-1,2,4-Benzothiadiazine, 3-(methylthio)-, 1,1-dioxide
- Synonyms:
- CAS NO:20926-33-4
- Molecular Formula: C8H8N2O2S2
- Molecular Weight:
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2H-1,2,4-Benzothiadiazine, 3-(methylthio)-, 1,1-dioxide(CAS DataBase Reference)
- NIST Chemistry Reference: 2H-1,2,4-Benzothiadiazine, 3-(methylthio)-, 1,1-dioxide(20926-33-4)
- EPA Substance Registry System: 2H-1,2,4-Benzothiadiazine, 3-(methylthio)-, 1,1-dioxide(20926-33-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 20926-33-4(Hazardous Substances Data)
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20926-33-4 Usage
Uses
Used in Ophthalmology:Methazolamide is used as a carbonic anhydrase inhibitor for the treatment of glaucoma. It helps in reducing intraocular pressure by decreasing the production of aqueous humor, thus preventing damage to the optic nerve and managing the symptoms of this eye condition.
Used in Neurology:
In the field of neurology, methazolamide is utilized for the treatment of certain types of epilepsy. Its inhibitory action on carbonic anhydrase contributes to the regulation of the body's physiological processes, aiding in the management of seizure activity.
Used in Travel and Recreation:
Methazolamide is employed to manage symptoms of altitude sickness, particularly edema. By alleviating the symptoms associated with high-altitude exposure, it helps individuals adapt more comfortably to changes in elevation and enjoy their travel and recreational activities.
Used in Cardiology:
Although still under investigation, methazolamide has shown potential therapeutic effects in heart failure. Its ability to modulate physiological processes may contribute to the management of this serious cardiac condition.
Used in Hematology:
Methazolamide has been studied for its potential benefits in sickle cell disease, a genetic disorder affecting red blood cells. Its role as a carbonic anhydrase inhibitor may offer new avenues for treatment and symptom management in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 20926-33-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,9,2 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.Calculate Digit Verification of CAS Registry Number 20926-33:
(7*2)+(6*0)+(5*9)+(4*2)+(3*6)+(2*3)+(1*3)=94
94 % 10 = 4
So 20926-33-4 is a valid CAS Registry Number.
20926-33-4Upstream product
20926-33-4Downstream Products
- 13338-00-6 2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide
- 42140-71-6 4-methyl-3-(methylthio)-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
- 42140-65-8 2-methyl-3-methylsulfanyl-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
- 13514-00-6 2-Methyl-3-oxo-2,3-dihydro-4H-1.2.4-benzothiadiazin-1.1-dioxid
- 93431-62-0 benzyl-(1,1-dioxo-1,2(4)-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-amine
- 20043-37-2 (1,1-dioxo-1,2(4)-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-phenyl-amine
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2H-1,2,4-Benzothiadiazine, 3-(methylthio)-, 1,1-dioxide
