Cas 209261-52-9,(3S)-4-(3-acetoxymethyl-3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)-2-[4-(3-pyridyl)phthalazin-1(2H)-on-2-yl]pyridine

209261-52-9

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Basic information

Product Name: (3S)-4-(3-acetoxymethyl-3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)-2-[4-(3-pyridyl)phthalazin-1(2H)-on-2-yl]pyridine
Synonyms: (3S)-4-(3-acetoxymethyl-3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)-2-[4-(3-pyridyl)phthalazin-1(2H)-on-2-yl]pyridine
CAS NO:209261-52-9
Molecular Formula:
Molecular Weight: 561.597
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (3S)-4-(3-acetoxymethyl-3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)-2-[4-(3-pyridyl)phthalazin-1(2H)-on-2-yl]pyridine(CAS DataBase Reference)
NIST Chemistry Reference: (3S)-4-(3-acetoxymethyl-3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)-2-[4-(3-pyridyl)phthalazin-1(2H)-on-2-yl]pyridine(209261-52-9)
EPA Substance Registry System: (3S)-4-(3-acetoxymethyl-3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)-2-[4-(3-pyridyl)phthalazin-1(2H)-on-2-yl]pyridine(209261-52-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 209261-52-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 209261-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,2,6 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 209261-52:
(8*2)+(7*0)+(6*9)+(5*2)+(4*6)+(3*1)+(2*5)+(1*2)=119
119 % 10 = 9
So 209261-52-9 is a valid CAS Registry Number.

209261-52-9Upstream product

66572-56-3 2-bromoisonicotinic acid

209261-52-9Downstream Products

209261-52-9Relevant academic research and scientific papers

Synthesis and biological activities of 1-pyridylisoquinoline and 1-pyridyldihydroisoquinoline derivatives as PDE4 inhibitors

Ukita, Tatsuzo,Sugahara, Masakatsu,Terakawa, Yoshihiro,Kuroda, Tooru,Wada, Kazuteru,Nakata, Aya,Kikkawa, Hideo,Ikezawa, Katsuo,Naito, Kazuaki

, p. 2347 - 2350 (2007/10/03)

A novel series of 1-pyridylisoquinoline and 1-pyridyldihydroisoquinoline derivatives has been prepared. These compounds showed potent PDE4 inhibitory activities and a broad margin between the Ki value of the rolipram binding affinity and the IC50 value of PDE4 inhibition. They also exhibited potent inhibitory activities toward LPS-induced TNF-α production in mice.

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