209329-11-3 Usage
Uses
(R)-2-Azetidinemethanol is used in the preparation of various compounds that are neprilysin inhibitors, which are useful in the treatment of hypertension, heart failure and renal disease alone or in combination therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 209329-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,3,2 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 209329-11:
(8*2)+(7*0)+(6*9)+(5*3)+(4*2)+(3*9)+(2*1)+(1*1)=123
123 % 10 = 3
So 209329-11-3 is a valid CAS Registry Number.
209329-11-3Relevant articles and documents
Efficient asymmetric synthesis of ABT-594; a potent, orally effective analgesic
Lynch, John K.,Holladay, Mark W.,Ryther, Keith B.,Bai, Hao,Hsiao, Chi-Nung,Morton, Howard E.,Dickman, Daniel A.,Arnold, William,King, Steven A.
, p. 2791 - 2794 (2007/10/03)
A concise asymmetric synthesis of (R)-2-chloro-5-(2- azetidinylmethoxy)pyridine (ABT-594) is presented in which the key intermediate t-butoxycarbonyl protected (2R)-azetidinylalcohol is obtained in three steps from the dibenzyl ester of D-aspartic acid in 44% yield and >99% ee.
