209347-44-4

Basic information

• Product Name: 1,8-diacetoxy-10-[(3,4-dimethoxybenzoyloxy)-3,4-dimethoxyphenylmethylene]-9(10H)-anthracenone
• CAS NO: 209347-44-4
• Molecular Weight: 638.628
• Mol File: 209347-44-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,8-diacetoxy-10-[(3,4-dimethoxybenzoyloxy)-3,4-dimethoxyphenylmethylene]-9(10H)-anthracenone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-diacetoxy-10-[(3,4-dimethoxybenzoyloxy)-3,4-dimethoxyphenylmethylene]-9(10H)-anthracenone(209347-44-4)
• EPA Substance Registry System: 1,8-diacetoxy-10-[(3,4-dimethoxybenzoyloxy)-3,4-dimethoxyphenylmethylene]-9(10H)-anthracenone(209347-44-4)

Safety Data

• Hazardous Substances Data: 209347-44-4(Hazardous Substances Data)

Upstream product

• 38165-75-2 1,8-diacetyloxy-9(10H)-anthracenone 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 

Relevant articles and documents

10-Benzoyl-1,8-dihydroxy-9(10H)-anthracenones: Synthesis and biological properties

The synthesis and biological properties of 10-benzoyl-1,8-dihydroxy-9(10H)-anthracenones are described. The compounds were evaluated for their ability to inhibit the growth of the human keratinocyte cell line HaCaT and the 5-lipoxygenase enzyme in bovine polymorphonuclear leukocytes. In addition, generation of hydroxyl radicals was determined as measured by deoxyribose degradation. The results obtained with the new compounds show that substitution with a 4-hydroxy (4f) or a 4-benzyloxy group (4i) at the phenyl ring of the C-10 substituent resulted in potent antiproliferative agents. No correlation was found between hydroxyl-radical formation and the 5-LO inhibitory or antiproliferative action of the compounds.