20935-64-2Relevant academic research and scientific papers
The Synthesis of Indan-1-ones and Isocoumarins
Carter, Rachel H.,Garson, Mary J.,Hill, Robert A.,Staunton, James,Sunter, David C.
, p. 471 - 479 (2007/10/02)
A flexible synthetic route leading via indan-1-ones to variously methylated and oxygenated isocoumarins is described.The indanones are prepared by alternative routes involving intramolecular Friedel-Crafts cyclisation of arylpropionic acids or pericyclic ring closure of acrylophenones.The influence of substitution on the rate of the pericyclic reaction is assessed.
