209467-30-1

Basic information

• Product Name: 3-{N^α-[6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-(benzyloxycarbonyl)amino}methyl)-2-pyridylcarbonyl]-L-histidinylamino}propionamide
• CAS NO: 209467-30-1
• Molecular Weight: 670.725
• Mol File: 209467-30-1.mol

Chemical Properties

• CAS DataBase Reference: 3-{N^α-[6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-(benzyloxycarbonyl)amino}methyl)-2-pyridylcarbonyl]-L-histidinylamino}propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{N^α-[6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-(benzyloxycarbonyl)amino}methyl)-2-pyridylcarbonyl]-L-histidinylamino}propionamide(209467-30-1)
• EPA Substance Registry System: 3-{N^α-[6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-(benzyloxycarbonyl)amino}methyl)-2-pyridylcarbonyl]-L-histidinylamino}propionamide(209467-30-1)

Safety Data

• Hazardous Substances Data: 209467-30-1(Hazardous Substances Data)

Upstream product

• 4726-85-6 β-alaninamide 
• 119802-78-7 (S)-2-[(6-{[Benzyloxycarbonyl-(2-benzyloxycarbonylamino-ethyl)-amino]-methyl}-pyridine-2-carbonyl)-amino]-3-(3H-imidazol-4-yl)-propionic acid 
• 209467-29-8 methyl N^α-[6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-benzyloxycarbonylamino}methyl)-2-pyridylcarbonyl]-L-histidinate 
• 138846-66-9 methyl 6-({N-[2-(benzyloxycarbonylamino)ethyl]-N-benzyloxycarbonylamino}methyl)pyridine-2-carboxylate 
• 72080-83-2 2-benzyloxycarbonylaminoethylamine 
• 119802-78-7 2-[(6-{[benzyloxycarbonyl-(2-benzyloxycarbonylamino-ethyl)-amino]-methyl}-pyridine-2-carbonyl)-amino]-3-(1H-imidazol-4-yl)-propionic acid 
• 209467-29-8 (S)-2-[(6-{[Benzyloxycarbonyl-(2-benzyloxycarbonylamino-ethyl)-amino]-methyl}-pyridine-2-carbonyl)-amino]-3-(3H-imidazol-4-yl)-propionic acid methyl ester 

Relevant articles and documents

Bleomycin model complex bearing a carbamoyl derived substituent capable of coordination to the chelated metal ion as a sixth ligand

A new, simple bleomycin (BLM) model compound bearing a carbamoyl group mimicking BLM's sugar-tagged carbamoyl moiety was synthesized and the physicochemical properties of its divalent metal complexes were studied. The Fe complex of the model compound exhi

Distal effect of amide and amino groups on the oxygen activation ability and rate of the redox reaction of simplified analogs of bleomycin

New simple bleomycin (BLM) model compounds, which bear a carbamide (1), bulky t-butyl (2), simple alkyl (3), or amino group (4) around the sixth coordination site, have been synthesized in order to study the effect of the distal substituents on the redox reaction and oxygen activation ability of the iron complexes. The carbamide group in 1 lowers the pK values of the all- amino donors of the ligand, which enhances complex formation. The oxygen activation ability of the Fe(II) complexes of 1, 2, 3, and 4, is 74, 69, 43, and 41%, respectively, of that of BLM. The rate of reduction of the Fe(III) complexes of the model compounds and BLM with a reducing agent is more than ten-times lower than that of the oxygenation and activation of the corresponding Fe(II) complexes, indicating the low turnover of the iron complexes of the model compounds and BLM in the reversible redox reaction.