209479-31-2

Upstream product

• 209479-25-4 (2R,3S,6S)-2,6-Dimethyl-7-(tetrahydro-pyran-2-yloxy)-heptane-1,3-diol 
• 209479-24-3 {(2S,3S)-3-[(S)-3-Methyl-4-(tetrahydro-pyran-2-yloxy)-butyl]-oxiranyl}-methanol 
• 209479-30-1 (4S,5S,8S)-8-((R)-2-Benzyloxy-1-methyl-ethyl)-4-hydroxy-5-methyl-oxocan-2-one 
• 209479-26-5 Bromo-acetic acid (1S,4S)-1-((R)-2-benzyloxy-1-methyl-ethyl)-4-methyl-5-(tetrahydro-pyran-2-yloxy)-pentyl ester 
• 209479-28-7 Bromo-acetic acid (1S,4S)-1-((R)-2-benzyloxy-1-methyl-ethyl)-4-methyl-5-oxo-pentyl ester 
• 209479-23-2 (E)-(S)-6-Methyl-7-(tetrahydro-pyran-2-yloxy)-hept-2-en-1-ol 
• 206998-26-7 (S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pentanal 
• 206998-25-6 (S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pentan-1-ol 
• 209479-22-1 (S)-4-Methyl-5-(tetrahydro-pyran-2-yloxy)-pentanoic acid ethyl ester 

Relevant academic research and scientific papers

A new stereoselective route to (-)-octalactin A based on intramolecular SmI2 promoted Reformatsky reaction

A novel stereoselective synthesis of the key left-hand fragment of (-)-octalactin A has been achieved from methyl (R)-3-hydroxy-2-methylpropionate employing SmI2 promoted intramolecular Reformatsky reaction of a δ-(bromoacetoxy)aldehyde as a key step.