2095156-13-9 Usage
Uses
Used in Pharmaceutical Research:
5-chloro-2-[(6-[4-(trifluoromethyl)phenoxy]pyridin-3-ylcarbonyl)amino]phenylboronic acid is used as a chemical tool for pharmaceutical research to study protein-drug interactions. Its ability to form reversible covalent bonds with certain biological molecules makes it a valuable asset in understanding and designing new drugs.
Used in Agrochemical Research:
In agrochemical research, 5-chloro-2-[(6-[4-(trifluoromethyl)phenoxy]pyridin-3-ylcarbonyl)amino]phenylboronic acid is used as a chemical tool for designing new crop protection agents. Its unique structural features allow it to potentially form bonds with biological targets relevant to pest control and crop protection.
Used in Materials Science:
5-chloro-2-[(6-[4-(trifluoromethyl)phenoxy]pyridin-3-ylcarbonyl)amino]phenylboronic acid is used as a component in the development of new materials with specific properties. Its structural characteristics can contribute to the creation of advanced materials for various applications.
Used in Catalysis:
In the field of catalysis, 5-chloro-2-[(6-[4-(trifluoromethyl)phenoxy]pyridin-3-ylcarbonyl)amino]phenylboronic acid is used as a catalyst or a catalyst precursor. Its ability to form reversible covalent bonds can be exploited to enhance the efficiency of chemical reactions.
Used in Organic Synthesis:
5-chloro-2-[(6-[4-(trifluoromethyl)phenoxy]pyridin-3-ylcarbonyl)amino]phenylboronic acid is used as a synthetic building block or reagent in organic synthesis. Its unique functional groups can be utilized to create a variety of complex organic molecules for different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 2095156-13-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,9,5,1,5 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2095156-13:
(9*2)+(8*0)+(7*9)+(6*5)+(5*1)+(4*5)+(3*6)+(2*1)+(1*3)=159
159 % 10 = 9
So 2095156-13-9 is a valid CAS Registry Number.
2095156-13-9Relevant academic research and scientific papers
Ogiyama, Tomoko,Yamaguchi, Mitsuhiro,Kurikawa, Nobuya,Honzumi, Shoko,Yamamoto, Yuka,Sugiyama, Daisuke,Takakusa, Hideo,Inoue, Shin-ichi
, p. 2234 - 2243 (2017)
Hormone sensitive lipase (HSL) has emerged as an attractive target for the treatment of dyslipidemia. We previously reported compound 1 as a potent and orally active HSL inhibitor. Although an attractive profile was demonstrated, subsequent studies revealed that compound 1 has a bioactivation liability. The oxygen-carbon linker in compound 1 was identified as being potentially responsible for reactive metabolite formation. By exchanging of this susceptible fragment was feasible, and a benzanilide derivative 6b with a decreased bioactivation liability was obtained. Further modification of the novel benzanilide scaffold resulted in the identification of compound 24b. Compound 24b exhibited potent HSL inhibitory activity (IC50 = 2 nM) with a significantly reduced bioactivation potential. Oral administration of compound 24b exhibited an antilipolytic effect on rats at 3 mg/kg.
