209523-08-0Relevant articles and documents
Palladium-catalyzed amination of 2,3,3-trifluoroallyl esters: Synthesis of trifluoromethylenamines via an intramolecular fluorine shift and CF3 group construction
Isa, Kazuki,Minakawa, Maki,Kawatsura, Motoi
, p. 6761 - 6764 (2015)
The palladium-catalyzed reaction of 2,3,3-trifluoroallyl esters with several types of amines afforded trifluoromethylenamines, which were formed by the addition of a nitrogen nucleophile at the C-2 position and the intramolecular construction of the trifluoromethyl group via the fluorine atom shift from the C-2 to the C-3 position.
Concise stereoselective synthesis of 1-perfluoroalkyl enamines via the addition of N-lithiated amines to enol ethers and their subsequent metalation to form new functionalized enamines
Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Bouvet, Denis,Rock, Michael H.
, p. 1797 - 1800 (1998)
Addition of lithium amides derived from a range of cyclic, sterically demanding, and chiral amines, to trifluoromethyl (Z)-enol ethers 1 and 4, provides stereoselectively the corresponding (Z)-enamines 3a-e and 7 in good yields. This reaction has been ext