20958-82-1

Basic information

• Product Name: 1,3-diphenylpyrrolo[2,1-a]isoquinoline-2-carboxamide
• CAS NO: 20958-82-1
• Molecular Formula: C₂₅H₁₈N₂O
• Molecular Weight: 362.4232
• Mol File: 20958-82-1.mol
• Article Data: 1

Chemical Properties

• Density: 1.21g/cm³
• Refractive Index: 1.675
• CAS DataBase Reference: 1,3-diphenylpyrrolo[2,1-a]isoquinoline-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-diphenylpyrrolo[2,1-a]isoquinoline-2-carboxamide(20958-82-1)
• EPA Substance Registry System: 1,3-diphenylpyrrolo[2,1-a]isoquinoline-2-carboxamide(20958-82-1)

Safety Data

• Hazardous Substances Data: 20958-82-1(Hazardous Substances Data)

Usage

Chemical class

Pyrroloisoquinoline compounds

Functional group

Carboxamide

Molecular structure

Complex

Potential applications

Medicinal chemistry

Biological activities

Anti-cancer and anti-inflammatory properties

Attraction

As a potential scaffold for novel pharmaceutical agents

Ongoing research

Synthesis and chemical properties

Objective

To explore potential therapeutic benefits

Upstream product

• 34008-39-4 1,3-diphenylpyrrolo<2,1-a>isoquinoline-2-carboxylic acid 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 20958-80-9 ethyl 1,3-diphenylpyrrolo<2,1-a>isoquinoline-2-carboxylate 

Downstream Products

• 20958-81-0 1,3-diphenylpyrrolo<2,1-a>isoquinoline 

Relevant articles and documents

Synthesis of 1,3-Disubstituted-pyrroloisoquinoline-2-carboxylic Acids, Esters and Amides

A number of 1,3-disubstituted pyrroloisoquinoline-2-carboxylic esters have been prepared using a variety of independent routes.The corresponding acids and a range of amides were subsequently synthesised.The primary amides were found to differ significantly from those reported to arise from the reaction between the anion of an isoquinoline Reissert compound and an α,β-unsaturated nitrile.Re-investigation has established that the latter reaction does not produce primary amides.The true nature of the products as 2-acyl-3-aminopyrroloisoquinolines was established using X-ray crystallography.