209588-75-0Relevant academic research and scientific papers
Chiral recognition in aggregates formed by chiral bola-amphiphiles
Ceccacci, Francesca,Profio, Pietro Di,Giansanti, Luisa,Mortera, Stefano Levi,Mancini, Giovanna,Sorrenti, Alessandro,Villani, Claudio
experimental part, p. 2117 - 2123 (2010/10/03)
The aggregates of three new isomeric chiral bola-amphiphiles have been taken into consideration as models for investigating chiral recognition in biological membranes. The recognition capabilities of the aggregates were explored following (by CD and HPLC
Preparation of α,ω-Diols of Long Carbon Chains and Their Use in Polyurethane Synthesis
Osakada, Kohtaro,Takenaka, Yasumasa,Yamaguchi, Isao,Yamamoto, Takakazu
, p. 1477 - 1482 (2007/10/03)
NaH promoted coupling reaction of HO(CH2)1O-TBDMS (1, TBDMS=SiMe2(t-Bu)) and Br(CH2)12O-TBDMS (2) followed by deprotection of the organosilyl groups affords HO(CH2)12O(CH2)12OH (5). 1,12-Dodecanediol reacts with an excess amount of 2 in the presence of NaH to give TBDMS-O(CH2)12O(CH2)12O(CH 2)12O-TBDMS (6) which is turned into HO(CH2)12O(CH2)12O(CH 2)12OH (7) by removal of the protecting groups. Similar 1 : 2 condensation of hydroquinone with 2 and with Br(CH2)6O-TBDMS (3) leads to formation of the corresponding α,α-diols, HO(CH2)12OC6H4O(CH2) 12OH (9) and HO(CH2)6OC6H4O(CH2) 6OH (11), respectively. The four new long α,ω-diols are isolated and characterized by means of IR and NMR spectroscopy as well as elemental analyses. Polyaddition reactions of 5, 7, 9, and 11 to 1,3-bis(isocyanatomethyl)benzene and 1,1′-methylenebis[4-isocyanatobenzene] give the corresponding poly(urethane)s in high yields. The obtained polymers, which were characterized by IR and NMR spectroscopy, have molecular weights over 20000 as determined from gel permeation chromatography using polystyrene standards.
