2097168-79-9

Basic information

• Product Name: 2-(4-((4-fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 2097168-79-9
• Molecular Weight: 328.191
• Mol File: 2097168-79-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-((4-fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-((4-fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(2097168-79-9)
• EPA Substance Registry System: 2-(4-((4-fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(2097168-79-9)

Safety Data

• Hazardous Substances Data: 2097168-79-9(Hazardous Substances Data)

Usage

Type of compound

boronic acid derivative

Use in organic synthesis

for the construction of carbon-carbon and carbon-heteroatom bonds

Potential antitumor activity

has been investigated for its use in cancer therapy

Use in pharmaceutical industry

for the development of new drugs

Use in materials science

for the synthesis of functional polymers

Value in research

a valuable building block for the synthesis of complex organic molecules and widely used in research laboratories.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 459-46-1 4-Fluorobenzyl bromide 
• 900911-39-9 1-bromo-4-((4-fluorobenzyl)oxy)benzene 
• 106-41-2 4-bromo-phenol 

Relevant articles and documents

Metal-Free and Redox-Neutral Conversion of Organotrifluoroborates into Radicals Enabled by Visible Light

Converting organoboron compounds into the corresponding radicals has broad synthetic applications in organic chemistry. To achieve these transformations, various strong oxidants such as Mn(OAc)3, AgNO3/K2S2O8, and Cu(OAc)2, in stoichiometric amounts are required, proceeding by a single-electron transfer mechanism. Established herein is a distinct strategy for generating both aryl and alkyl radicals from organotrifluoroborates through an SH2 process. This strategy is enabled by using water as the solvent, visible light as the energy input, and diacetyl as the promoter in the absence of any metal catalyst or redox reagent, thereby eliminating metal waste. To demonstrate its synthetic utility, an efficient acetylation to prepare valuable aryl (alkyl) methyl ketones is described and applications to construct C?C, C?I, C?Br, and C?S bonds are also feasible. Experimental evidence suggests that triplet diacetyl serves as the key intermediate in this process.