209725-87-1Relevant articles and documents
Toward supramolecular ion channels formed by oligonucleotide analogs: Hydrophobic guanine dimers
Chen, Li,Sakai, Naomi,Moshiri, Sara T.,Matile, Stefan
, p. 3627 - 3630 (2007/10/03)
In this model study toward supramolecular channels formed by oligonucleotide analogs, we describe the synthesis of hydrophobic guanine dimers 1 - 4. We found that the solubility of guanine dimers 1 - 4 is significantly reduced compared to hydrophobic (iso)guanosine monomers and independent of the nature of substituents at the exocyclic amine. This indicates that the (deoxy)ribose is important to form soluble, ionophoric G- quartets.