209730-34-7Relevant academic research and scientific papers
Microwave assisted synthesis and antifungal activity of 1,2,4-triazine, 1,2,4-triazole, tetrazole and pyrazole derivatives
Kidwai, Mazaahir,Goel, Yogesh,Kumar, Rajesh
, p. 174 - 179 (2007/10/03)
The condensation reactions of 2-hydrazino-4-methylquinoline with diethyl oxalate, ethyl bromoacetate, aromatic aldehydes, acetic anhydride, nitrous acid and different acetophenones followed by DMF and POCl3 under microwave irradiation and by conventional methods are described. The reaction rate is enhanced tremendously under microwave irradiation as compared to conventional method with improved yields. All the newly synthesised compounds have been screened for antifungal activity against fungi A. niger andA.flavous.
Microwave assisted synthesis and pharmacological screening of 3-(substituted phenyl)-5-methylquinolino-1,2,4-triazines
Kidwai, Mazaahir,Kohli, Seema,Goel, A. K.,Dubey, M. P.
, p. 1063 - 1065 (2007/10/03)
A series of quinolinotriazines have been synthesized by condensation of 2-hydrazino-4-methylquinoline 3 with aromatic aldehydes followed by nitrosation with sodium nitrite in acetic acid leading to ring closure under microwave irradiation.
