209804-26-2

Upstream product

• 1129-28-8 3-methoxycarbonylbenzyl bromide 

Downstream Products

• 209804-82-0 (3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-5-[3-(2-pyridin-2-yl-acetyl)-benzyl]-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-6-one 
• 1053244-04-4 (3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-5-(3-[1,2,4]triazol-1-ylmethyl-benzyl)-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-6-one 
• 1053263-85-6 (3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-5-(3-pyrazol-1-ylmethyl-benzyl)-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-6-one 
• 209804-81-9 3-{(3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-6-oxo-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-5-ylmethyl}-N-methoxy-N-methyl-benzamide 
• 209804-31-9 2-(3-{(3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-6-oxo-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-5-ylmethyl}-phenyl)-acetamide 
• 209804-29-5 (3-{(3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-6-oxo-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-5-ylmethyl}-phenyl)-acetonitrile 
• 209804-28-4 (3aS,4R,8R,8aS)-4,8-Dibenzyl-5-(3-bromomethyl-benzyl)-2,2-dimethyl-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-6-one 
• 209804-37-5 {3-[(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-3-(1H-indazol-5-ylmethyl)-2-oxo-[1,3]diazepan-1-ylmethyl]-phenyl}-acetic acid methyl ester 
• 209804-33-1 3-[(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-3-(1H-indazol-5-ylmethyl)-2-oxo-[1,3]diazepan-1-ylmethyl]-benzoic acid 
• 209804-80-8 3-{(3aS,4R,8R,8aS)-4,8-Dibenzyl-2,2-dimethyl-6-oxo-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-5-ylmethyl}-benzoic acid 
• 209804-27-3 (3aS,4R,8R,8aS)-4,8-Dibenzyl-5-(3-hydroxymethyl-benzyl)-2,2-dimethyl-7-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazol-5-ylmethyl]-hexahydro-1,3-dioxa-5,7-diaza-azulen-6-one 
• 1054645-44-1 3-[(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-3-(1H-indazol-5-ylmethyl)-2-oxo-[1,3]diazepan-1-ylmethyl]-benzoic acid methyl ester 

Relevant academic research and scientific papers

Nonsymmetric P2/P2' cyclic urea HIV protease inhibitors. Structure- activity relationship, bioavailability, and resistance profile of monoindazole-substituted P2 analogues

Using the structural information gathered from the X-ray structures of various cyclic urea/HIVPR complexes, we designed and synthesized many nonsymmetrical P2/P2'-substituted cyclic urea analogues. Our efforts concentrated on using an indazole as one of t