209852-23-3

Upstream product

• 209852-35-7 5-Azido-4-(tert-butyl-diphenyl-silanyloxy)-pentan-2-ol 
• 92775-36-5 tert-butyldimethyl(pent-4-en-2-yloxy)silane 
• 209852-22-2 1-Azido-4-(tert-butyl-dimethyl-silanyloxy)-pentan-2-ol 
• 209852-33-5 C₂₇H₄₃N₃O₂Si₂ 
• 209852-21-1 2-{2-[(tert-butyldimethylsilyl)oxy]propyl}oxirane 
• 111957-98-3 Pent-4-en-2-ol 

Downstream Products

• 209852-27-7 2-({[(2R,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl]-carbamoyl}-methyl)-4-(tert-butyl-diphenyl-silanyloxy)-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 209852-28-8 4-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-2-({[(2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl]-carbamoyl}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 209852-25-5 4-(tert-Butyl-diphenyl-silanyloxy)-2-ethoxycarbonylmethyl-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 209852-26-6 4-(tert-Butyl-diphenyl-silanyloxy)-2-carboxymethyl-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Design and synthesis of bio-isosteres of thymidine triphosphate

This paper describes the design and synthesis of potential isosteres of triphosphates which should show enhanced metabolic stability and lipophilicity compared to triphosphates. The triphosphate isosteres were then linked to nucleosides and evaluated for their inhibitory activity against HIV infection.