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N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-(1-isopropylpiperidin-4-yl)benzofuran-4-carboxamide is a complex organic compound with a diverse structure. It features multiple functional groups, such as a dihydropyridin-3-ylmethyl group, an ethylamino group, a piperidin-4-yl group, an oxo group, and a carboxamide group. The intricate arrangement of these groups suggests that the compound may have potential pharmaceutical applications, given its capacity to interact with biological systems. However, further research and testing are required to ascertain its specific properties and possible uses.

2098546-05-3

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2098546-05-3 Usage

Uses

Used in Pharmaceutical Industry:
N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-ethyl-6-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-(1-isopropylpiperidin-4-yl)benzofuran-4-carboxamide is used as a potential pharmaceutical agent for its complex structure and the presence of various functional groups. These features may allow it to engage with biological systems in ways that could be beneficial for medicinal purposes, such as targeting specific receptors or enzymes. The exact application would depend on the outcomes of further research into its properties and interactions with biological targets.

Check Digit Verification of cas no

The CAS Registry Mumber 2098546-05-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,9,8,5,4 and 6 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2098546-05:
(9*2)+(8*0)+(7*9)+(6*8)+(5*5)+(4*4)+(3*6)+(2*0)+(1*5)=193
193 % 10 = 3
So 2098546-05-3 is a valid CAS Registry Number.

2098546-05-3Downstream Products

2098546-05-3Relevant academic research and scientific papers

Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma

Lu, Biao,Shen, Xiaodong,Zhang, Lei,Liu, Dong,Zhang, Caihua,Cao, Jingsong,Shen, Ru,Zhang, Jiayin,Wang, Dan,Wan, Hong,Xu, Zhibin,Ho, Ming-Hsun,Zhang, Minsheng,Zhang, Lianshan,He, Feng,Tao, Weikang

, p. 98 - 102 (2018/02/19)

A novel series of benzofuran derived EZH2 inhibitors were discovered through a scaffold hopping approach based on the clinical compound of EPZ-6438. Further rational structure-activity relationship exploration and optimization led to the discovery of more potent EZH2 inhibitors with oral bioavailability in mice and rats. A lead compound EBI-2511 (compound 34) demonstrated excellent in vivo efficacy in Pfeiffer tumor Xenograft models in mouse and is under preclinical development for the treatment of cancers associated with EZH2 mutations.

BENZOFURAN DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN MEDICINE

-

, (2018/10/11)

The present invention relates to a benzofuran derivative, a preparation method thereof and a use thereof in medicine. In particular, the present invention relates to the benzofuran derivative as shown by general formula (I), the preparation method thereof, a pharmaceutical composition containing the derivative, and uses thereof as an EZH2 inhibitor and in the prevention and/or treatment of diseases such as tumours and cancers, etc., and in particular uses thereof in the prevention and/or treatment of non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, follicular lymphoma and synovial sarcoma, wherein the definitions of the substituents in the general formula (I) are the same as those defined in the description.

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