2098583-31-2Relevant academic research and scientific papers
PYRIDO OXAZINE AMINO DERIVATIVES AS ALK5 INHIBITORS
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Paragraph 0427-0429, (2022/01/24)
The present invention relates to a compound of general formula (I) inhibiting the growth factor receptor transforming β (TGF-β) type I (ALK5), methods for preparing these compounds, pharmaceutical compositions containing them and their therapeutic use. The compounds according to the invention may be useful in the treatment of diseases or conditions associated with the disruption of the ALK5 signaling pathway in a mammal.
AZETIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
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Paragraph 0099; 0100, (2018/08/29)
The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, infl
COMPOUND, COMPOSITIONS, AND METHODS
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, (2017/08/01)
Compounds having activity as LRRK2 inhibitors are disclosed. The compounds are of formula (I) including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
