209977-56-0 Usage
Description
(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4-yl]-propionic Acid Sesquihydrate is a white crystalline solid that serves as a selective inhibitor of [3H]-AMPA binding in rat brain membranes. It exhibits minimal affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as indicated by the binding of [3H]-CPP, [3H]-gly, or [3H]-MK-801. (r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]-propionic Acid Sesquihydrate also selectively antagonizes AMPA-induced responses in rat cortical wedge preparations, distinguishing it from kainate-, quisqualate-, and NMDA-induced responses.
Uses
Used in Pharmaceutical Industry:
(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4-yl]-propionic Acid Sesquihydrate is used as a selective inhibitor for [3H]-AMPA binding in rat brain membranes for the development of potential therapeutic agents targeting neurological disorders and conditions related to the AMPA receptor.
Used in Research Applications:
In the field of neuroscience research, (r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4-yl]-propionic Acid Sesquihydrate is utilized as a tool to study the role of AMPA receptors in various brain functions and to investigate the underlying mechanisms of neurological diseases associated with these receptors.
Used in Drug Development:
(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4-yl]-propionic Acid Sesquihydrate is employed in the development of novel drugs that aim to modulate AMPA receptor activity, potentially leading to treatments for conditions such as epilepsy, Alzheimer's disease, and other neurological disorders where AMPA receptor dysfunction is implicated.
Check Digit Verification of cas no
The CAS Registry Mumber 209977-56-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,9,7 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 209977-56:
(8*2)+(7*0)+(6*9)+(5*9)+(4*7)+(3*7)+(2*5)+(1*6)=180
180 % 10 = 0
So 209977-56-0 is a valid CAS Registry Number.