210037-55-1

Basic information

• Product Name: Benzonitrile, 2-hydroxy-4-(hydroxymethyl)- (9CI)
• Synonyms: Benzonitrile, 2-hydroxy-4-(hydroxymethyl)- (9CI);2-hydroxy-4-(hydroxymethyl)benzonitrile
• CAS NO: 210037-55-1
• Molecular Formula: C₈H₇NO₂
• Molecular Weight: 149.14668
• Product Categories: ALDEHYDE
• Mol File: 210037-55-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzonitrile, 2-hydroxy-4-(hydroxymethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 2-hydroxy-4-(hydroxymethyl)- (9CI)(210037-55-1)
• EPA Substance Registry System: Benzonitrile, 2-hydroxy-4-(hydroxymethyl)- (9CI)(210037-55-1)

Safety Data

• Hazardous Substances Data: 210037-55-1(Hazardous Substances Data)

Upstream product

• 89939-36-6 4-(hydroxymethyl)-2-nitrobenzonitrile 
• 874-89-5 4-Cyanobenzyl alcohol 
• 157942-12-6 methyl 3-hydroxy-4-iodobenzoate 
• 63435-16-5 3-hydroxy-4-aminobenzoic acid methyl ester 
• 2374-03-0 4-aminosalicylic acid 
• 6520-87-2 methyl 4-cyano-3-hydroxybenzoate 

Downstream Products

• 210037-56-2 4-bromomethyl-2-hydroxy-benzonitrile 
• 210037-57-3 2-hydroxy-4-imidazol-1-ylmethyl-benzonitrile 

Relevant articles and documents

Diaryl ether inhibitors of farnesyl-protein transferase

Imidazolemethyl diaryl ethers are potent inhibitors of farnesyl-protein transferase. The SNAr displacement reaction used to prepare these diaryl ethers was amenable to rapid parallel synthesis of FPTase inhibitors. The use of a broad range of c

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.