210098-00-3

Basic information

• Product Name: 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde
• Synonyms: 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde
• CAS NO: 210098-00-3
• Molecular Formula: C6H4Cl2OS
• Molecular Weight: 195.06636
• Mol File: 210098-00-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde(210098-00-3)
• EPA Substance Registry System: 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde(210098-00-3)

Safety Data

• Hazardous Substances Data: 210098-00-3(Hazardous Substances Data)

Usage

General Description

2,5-Dichloro-4-Methylthiophene-3-carbaldehyde is a chemical compound with the molecular formula C7H4Cl2OS. It is a yellow liquid with a strong odor, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde is known for its strong oxidizing properties, and it can react violently with a wide range of other chemicals. It is important to handle 2,5-Dichloro-4-Methylthiophene-3-carbaldehyde with care, as it can be hazardous to human health and the environment.

Relevant articles and documents

Pyridylfuran and pyridylthiophene compounds

A compound of the formula: and its pharmaceutically effective salts, wherein R1 and R2 are independently selected from the following: (a) hydrogen, halo, R5-, C2-6 alkenyl, C2-6 alkynyl, hydroxy-R5-, R5-O-R5-, or the like; (b) Ar-, Ar-R5-, Ar-C2-6 alkenyl, Ar-C2-6 alkynyl, Ar-O-, Ar-O-R5- or the like; (c) R5-C(O)-, -NO2, cyano, NH2-C(O)-, R5-NH-C(O)-, (R5)2-N-C(O)-, Ar-C(O)- or the like; and (d) R5-C(O)-NH-, Ar-C(O)-NH- or the like; wherein Ar is optionally substituted aryl or heteroaryl such as phenyl and pyridyl; and wherein R5 is optionally halo-substituted C1-6 alkyl; R3 is selected from the following: (e) cyano, formyl, tetrazolyl, triazolyl, imidazolyl, oxazolyl, thiazolyl, R5-C(O)-, C2-6 alkenyl-C(O)-, C2-6 alkynyl-C(O)-, R5-C(O)-R5-, or the like; (f) R5-C(O)-NH-, Ar-C(O)-NH-, or the like; (g) R5-S-, R5-S(O)-, R5-NH-S(O)2-, or the like; and (h) Ar-C(O)-, Ar-R5-C(O)-, Ar-C2-6 alkenylene-C(O)- or the like; or two of R1, R2 and R3 together form a group of the formula -A1-B1-A2- or -A1-B1-A3-B2-A2- such as cyclic alkyl optionally substituted with oxo; R4 is hydrogen, halo, R5-C(O)- and the like; X is O, S, S(O) or S(O)2; m is 0, 1, 2, 3 or 4. The present invention also provides processes for the preparation thereof, the use thereof in treating cytokine mediated diseases and/or cell adhesion molecule (CAM) mediated diseases and pharmaceutical compositions for use in such therapy.