210174-73-5

Basic information

• Product Name: 1,5-Dideoxy-1,5-imino-L-fucitol hydrochloride
• Synonyms: 1,5-Dideoxy-1,5-imino-L-fucitol hydrochloride;(2S,3R,4S,5R)-2-Methylpiperidine-3,4,5-triol hydrochloride;(2S,3R,4S,5R)-2-Methyl-3,4,5-piperidinetriol;1,5-Dideoxy-1,5-iMino-L-fucitol;(2S,3R,4S,5R)-2-Methyl-3,4,5-trihydroxypiperidine hydrochloride;Deoxyfuconojirimycin hydrochloride, (2S,3R,4S,5R)-2-Methylpiperidine-3,4,5-triol hydrochloride
• CAS NO: 210174-73-5
• Molecular Formula: C6H13NO3.ClH
• Molecular Weight: 183.634
• Product Categories: Carbohydrates & Derivatives;Glycosidase Inhibitors;Inhibitors
• Mol File: 210174-73-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 155-157°C
• Appearance: /
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• CAS DataBase Reference: 1,5-Dideoxy-1,5-imino-L-fucitol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Dideoxy-1,5-imino-L-fucitol hydrochloride(210174-73-5)
• EPA Substance Registry System: 1,5-Dideoxy-1,5-imino-L-fucitol hydrochloride(210174-73-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 210174-73-5(Hazardous Substances Data)

Usage

Chemical Properties

Tan Solid

Uses

A powerful and specific inhibitor of several alpha-L-fucosidases.

Upstream product

• 23843-32-5 2,3-Isopropylidene-D-gulono-γ-lactone 
• 2484-55-1 2,3-O-isopropylidene-1,6-bis-O-(p-toluenesulfonyl)-α-L-sorbofuranose 
• 910222-14-9 N-benzyloxycarbonyl-1,5,6-trideoxy-1,5-imino-D-glucitol 
• 150965-62-1 6-Deoxy-2,3-O-isopropylidene-5-O-trifluoromethanesulfonyl-D-gulono-1,4-lactone 
• 142204-18-0 5-Azido-5,6-dideoxy-2,3-O-isopropylidene-L-mannono-γ-lactone 
• 142204-16-8 6-Bromo-6-deoxy-2,3-O-isopropylidene-D-gulono-γ-lactone 
• 142236-34-8 6-Deoxy-1,2-O-isopropylidene-L-mannono-γ-lactam 
• 142204-17-9 6-Deoxy-2,3-O-isopropylidene-D-gulono-γ-lactone 
• 150965-62-1 Trifluoro-methanesulfonic acid (S)-1-((3aS,4S,6aS)-2,2-dimethyl-6-oxo-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-ethyl ester 
• 142204-14-6 5-Azido-5,6-dideoxy-2,3-O-isopropylidene-D-mannono-γ-lactone 
• 142204-12-4 6-Bromo-6-deoxy-2,3-O-isopropylidene-L-gulono-γ-lactone 
• 142204-13-5 6-Deoxy-2,3-O-isopropylidene-L-gulono-γ-lactone 
• 94840-08-1 2,3-O-isopropylidene-L-gulono-γ-lactone 
• 142204-15-7 6-Deoxy-1,2-O-isopropylidene-D-mannono-γ-lactam 

Relevant articles and documents

Preparation of 1,6-di-deoxy-D-galacto and 1,6-di-deoxy-L-altro nojirimycin derivatives by aminocyclization of a 1,5-dicarbonyl derivative

Iminosugars are known glycosidase inhibitors which are the subject of drug development efforts against several diseases. The access to structurally-related families of iminosugars is of primary importance for running structure-activity relationship studie

Synthesis of, and lack of inhibition of a rhamnosidase by, both enantiomers of deoxyrhamnojirimycin and rhamnolactam: β-Mannosidase inhibition by δ-lactams

Synthesis of both enantiomers of deoxyrhamnojirimycin and rhamnonolactam from D- and L-gulonolactones are described. The effects as inhibitors of the enantiomeric deoxyrhamnojirimycins and rhamnonolactams on human liver glycosidases are compared with deoxymannojirimycin and mannonolactam. No significant inhibition of the activity of naringinase (an α-L-rhamnosidase) was caused by any of these compounds.