21022-88-8Relevant academic research and scientific papers
Selective hydroxy group protection of gallic acid
Zhu, Jieping,Chastanet, Jacqueline,Beugelmans, Rene
, p. 2479 - 2486 (1996)
An efficient procedure allowing selective differentiation of the 4-hydroxy group of methyl gallate was reported.
Synthesis and structure of oxacalix[2]arene[2]triazines of an expanded π-electron-deficient cavity and their interactions with anions
Li, Sen,Fa, Shi-Xin,Wang, Qi-Qiang,Wang, De-Xian,Wang, Mei-Xiang
supporting information; scheme or table, p. 1860 - 1867 (2012/04/23)
Novel macrocyclic anion receptors based on the principle of anion-π interactions were reported. By means of both post-macrocyclization modification protocol and the stepwise fragment coupling approach, functionalized oxacalix[2]arene[2]triazines bearing two other electron-deficient (hetero)aromatic rings on the lower rim were efficiently synthesized. The resulting oxacalix[2]arene[2]triazine macrocyclesadopt 1,3-alternate conformation, yielding therefore an expanded electron-deficient cavity or space consisting of two triazine rings and two appending aromatic rings. Spectroscopic titration study showed the selective interaction of the pentafluorophenyl- substituted oxacalix[2]arene[2]triazine with azide and fluoride in solution with the binding constants (K1:1) ranging from 1.33 × 10 3 to 3.52 × 103 M-1.
Synthesis of Patent Blue derivatized hydrophilic dendrons dedicated to sentinel node detection in breast cancer
Kueny-Stotz, Marie,Mamlouk-Chaouachi, Hind,Felder-Flesch, Delphine
scheme or table, p. 2906 - 2909 (2011/06/21)
In the last decade, methods for the precise localization of sentinel lymph node (SLN) have drawn tremendous attention by oncology surgeons and researchers in the field of medical diagnosis. The accurate identification and characterization of lymph nodes by imaging has important therapeutic and prognostic significance in patients with newly diagnosed cancers. The SLN is the first lymph node that receives lymphatic drainage from the site of a primary tumor. Two biocompatible dendronized phosphonates, one bearing a Patent Blue (PB VF) dye at its periphery, where synthesized. Indeed, such a blue dye is currently injected to label the lymph node system for its per-operative detection. Therefore, developing chemistry of Patent Blue VF to optimize early diagnosis is of great current interest.
A simple method for controlling dendritic architecture and diversity: A parallel monomer combination approach
Freeman,Chrisstoffels,Frechet
, p. 7612 - 7617 (2007/10/03)
A novel parallel monomer combination approach to manipulating the architectural disposition of dendritic macromolecules is described. It harnesses the synthetic speed and power of the double-stage convergent growth approach and classical parallel synthesi
