2103-44-8Relevant academic research and scientific papers
Design and synthesis of novel pyridopyrimidine derivatives with anchoring non-coplanar aromatic extensions of EGFR inhibitory activity
Eissa, Amal A.M.,Aljamal, Kholoud F.M.,Ibrahim, Hany S.,Abdelrasheed Allam, Heba
, (2021)
The present study describes the synthesis of three series of 4-substituted pyridopyrimidin derivatives 4a-h, 5a-d. 6a-d, starting from 2-amino-6-(4-methoxyphenyl)-4-(4-(substituted) phenyl)nicotinonitrile 2a-d via the reaction with N,N-dimethyl-N-' substi
