2103-48-2Relevant academic research and scientific papers
Novel synthesis of 1-substituted-4-imidazolecarboxylates via solvent-free cycloaddition reaction between formamidines and isocyanides
Cao, Han,Bie, Fu-sheng,Liu, Xue-jing,Han, Ying,Ma, Jie,Shi, Yi-jun,Yan, Peng,Sun, Chao-yue,Wang, Hai-meng
, (2020/04/27)
A simple and efficient protocol for cyclization between formamidines and ethyl isocyanoacetate has been described in the absence of metal catalyst and solvent. A series of 1-substituted-4-imidazolecarboxylates were synthesized in moderate to good yields with DABCO as base additive.
Oxo/Imido heterometathesis reactions catalyzed by a silica-supported tantalum imido complex
Zhizhko, Pavel A.,Zhizhin, Anton A.,Belyakova, Olga A.,Zubavichus, Yan V.,Kolyagin, Yuriy G.,Zarubin, Dmitry N.,Ustynyuk, Nikolai A.
, p. 3611 - 3617 (2013/07/26)
Grafting Ta(=NtBu)(CH2CMe2Ph)3 onto the surface of silica partially dehydroxylated at 300°C leads to the formation of the surface imido complex (≡SiO)2Ta(=N tBu)(CH2CMe2Ph) as a major species, which was characterized with EXAFS, 13C CP/MAS NMR, diffuse reflectance FTIR, elemental analyses, and chemical reactivity. The obtained material acts as an efficient heterogeneous catalyst for various oxo/imido heterometathesis transformations: imidation of ketones and DMF with N-sulfinylamines and condensation of N-sulfinylamines into sulfurdiimines and phenyl isocyanate into diphenylcarbodiimide.
Molybdenum-mediated imido-transfer reaction of N-sulfinylamines with dimethylformamide
Zhizhin, Anton A.,Zarubin, Dmitry N.,Ustynyuk, Nikolai A.
experimental part, p. 165 - 166 (2009/09/06)
Dimethylformamide undergoes molybdenum-mediated metathetical imido-deoxygenation with ortho-substituted by donor atoms N-sulfinylanilines affording formamidines; N-sulfinylamines undergo molybdenum-mediated condensation into sulfurdiimines.
A Versatile New Synthesis of Quinolines and Related Fused Pyridines. Part 5. The Synthesis of 2-Chloroquinoline-3-carbaldehydes
Meth-Cohn, Otto,Narine, Bramha,Tarnowski, Brian
, p. 1520 - 1530 (2007/10/02)
Acetanilides are converted into 2-chloroquinoline-3-carbaldehydes in good yield by the action of Vilsmeier's reagent in phosphoryl chloride solution.The reaction is shown to involve successive conversion of the acetanilide into an imidoyl chloride and then an N-(α-chlorovinyl)aniline.The latter enamine is diformylated at its β-position and subsequently cyclised to the chloroquinolinecarbaldehyde.The diformylated intermediates may be isolated in several cases and separately cyclised with polyphosphoric acid.
