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4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-b-D-glucopyranoside, Potassium Salt is a white crystalline solid that serves as a fluorogenic substrate used in the diagnosis of GM2 gangliosidoses, a group of inherited lysosomal storage disorders. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) lead to various clinical and biochemical types of GM2 gangliosidosis, including Tay Sachs disease, Sandhoff disease, and other forms.

210357-38-3

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210357-38-3 Usage

Uses

Used in Diagnostic Applications:
4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-b-D-glucopyranoside, Potassium Salt is used as a fluorogenic substrate for the detection and diagnosis of GM2 gangliosidoses in leukocytes. This application is crucial for identifying genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B), which are responsible for the various clinical and biochemical types of GM2 gangliosidosis.
Used in Medical Research:
In the field of medical research, 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-b-D-glucopyranoside, Potassium Salt is used as a research tool to study the enzymatic activity of b-hexosaminidase isozymes and their role in the pathogenesis of GM2 gangliosidoses. This helps in understanding the molecular mechanisms underlying these disorders and contributes to the development of potential therapeutic strategies.
Used in Pharmaceutical Industry:
4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-b-D-glucopyranoside, Potassium Salt is used in the pharmaceutical industry for the development and quality control of drugs targeting GM2 gangliosidoses. As a fluorogenic substrate, it can be employed to assess the efficacy of potential therapeutic agents and monitor their progress in preclinical and clinical trials.
Used in Genetic Counseling:
In the context of genetic counseling, 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-b-D-glucopyranoside, Potassium Salt is used to identify carriers of the genetic mutations associated with GM2 gangliosidoses. This information is valuable for couples who are planning to have children and want to understand the risks of passing on these genetic disorders to their offspring.

Check Digit Verification of cas no

The CAS Registry Mumber 210357-38-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,3,5 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 210357-38:
(8*2)+(7*1)+(6*0)+(5*3)+(4*5)+(3*7)+(2*3)+(1*8)=93
93 % 10 = 3
So 210357-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO11S.K/c1-8-5-14(21)29-12-6-10(3-4-11(8)12)28-18-15(19-9(2)20)17(23)16(22)13(30-18)7-27-31(24,25)26;/h3-6,13,15-18,22-23H,7H2,1-2H3,(H,19,20)(H,24,25,26);/q;+1/p-1/t13?,15-,16+,17+,18+;/m0./s1/rC18H20KNO11S/c1-8-5-14(22)29-12-6-10(3-4-11(8)12)28-18-15(20-9(2)21)17(24)16(23)13(30-18)7-27-32(25,26)31-19/h3-6,13,15-18,23-24H,7H2,1-2H3,(H,20,21)/t13?,15-,16+,17+,18+/m0/s1

210357-38-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside Potassium Salt

1.2 Other means of identification

Product number -
Other names 4-Methylumbelliferyl 2-acetamido-2-deoxy-6-O-sulfo-β-D-glucopyranoside potassium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:210357-38-3 SDS

210357-38-3Upstream product

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