210366-26-0

Upstream product

• 586-96-9 Nitrosobenzene 
• 55533-24-9 L-N-tert-butoxycarbonyl-p-aminophenylalanine 
• 7738-30-9 4-azophenyl-L-phenylalanine 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 

Relevant academic research and scientific papers

Optical-controlled antibacterial agent composed of linear-chain cation oligopeptides and multi-arm beta-cyclodextrin

The invention discloses an optical-controlled antibacterial agent which is composed of linear-chain cation oligopeptides and multi-arm beta-cyclodextrin and utilizes illumination for regulating antibacterial activity, and belongs to the technical field of antibacterial materials. According to the optical-controlled antibacterial agent composed of the photo-responsive linear-chain cation oligopeptides and the multi-arm beta-cyclodextrin, the azobenzene-containing linear-chain cation oligopeptides and the multi-arm beta-cyclodextrin form a cross-linked aggregate through "subject-object" recognition. The linear-chain cation oligopeptides and the multi-arm beta-cyclodextrin have obviously different antibacterial activity in aggregation and disaggregation states. According to the optical-controlled antibacterial agent, a photo-isomerization characteristic of azobenzene conformations of the linear-chain cation oligopeptides is utilized for adjusting aggregation and disaggregation of "subject-object" recognition between azobenzene and the cyclodextrin to control formation and disintegration of the cross-linked aggregate, and thus the purpose of utilizing illumination for adjusting the antibacterial activity of the linear-chain cation oligopeptides is achieved; and that is to say, the optical-controlled antibacterial agent can change antibacterial activity under light irradiation, andthe antibacterial property of the optical-controlled antibacterial agent can be manually intervened in the aspects of time and space.

Smart hydrogels from laterally-grafted peptide assembly

Small peptides carrying laterally-grafted azobenzene units self-assemble into photo-responsive hydrogels which are applied as a smart matrix for controlling the dye molecules release. We demonstrate that a delicate balance among peptides interactions plays a pivotal role in the photo-responsive gel-sol transition.