210428-12-9Relevant academic research and scientific papers
Synthesis of β-ketophosphonate analogs of glutamyl and glutaminyl adenylate, and selective inhibition of the corresponding bacterial aminoacyl-tRNA synthetases
Balg, Christian,Blais, Sebastien P.,Bernier, Stephane,Huot, Jonathan L.,Couture, Manon,Lapointe, Jacques,Chenevert, Robert
, p. 295 - 304 (2007)
The aminoacyl-β-ketophosphonate-adenosines (aa-KPA) are stable analogs of the aminoacyl adenylates, which are high-energy intermediates in the formation of aminoacyl-tRNA catalyzed by aminoacyl-tRNA synthetases (aaRS). We have synthesized glutamyl-β-ketop
Synthesis of a tripeptide derivative containing the Gln-Arg hydroxyethylene dipeptide isostere
Brewer, Matthias,James, Clint A.,Rich, Daniel H.
, p. 4779 - 4782 (2007/10/03)
(Chemical Equation Presented) The protected hydroxyethylene dipeptide isostere of Gln-Arg and the tripeptide derivative 1 were synthesized as components of potential peptidase inhibitors.
