210479-91-7

Upstream product

• 72471-11-5 methyl 6-deoxy-6-amino-2,3,4-tri-O-benzyl-α-D-glucopyranoside 
• 210479-86-0 (2R,3R,4R,5R)-3,4-Bis-benzyloxy-5-(tert-butoxycarbonylamino-methyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 
• 184017-37-6 1-O-acetyl-3,4-di-O-benzyl-6-[(tert-butyloxycarbonyl)amino]-2,5-[(tert-butyloxycarbonyl)imino]-2,5,6-trideoxy-D-glucitol 
• 184017-39-8 (2R,3R,4R,5S)-3,4-Bis-benzyloxy-2-(tert-butoxycarbonylamino-methyl)-5-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis of ester-and amide-linked pseudo-azadisaccharides via coupling of D-glucose with 6-amino-6-deoxy-2,5-imino-D-glucitol

Hydrolytically-resistant pseudodisaccharides incorporating an azafuranose have been prepared by coupling 6-amino-2,5-imino-D-glucitol derivatives with D-glucose, either through an ester or an amide bond. Synthesis of the azasugar templates was achieved by nucleophilic opening of a C2 symmetric bis-aziridine deriving from D-mannitol.